A PSMA-targeted theranostic agent for photodynamic therapy. Water saturation shift referencing (WASSR) for chemical exchange saturation transfer (CEST) experiments. CEST theranostics: label-free MR imaging of anticancer drugs. High-throughput screening of chemical exchange saturation transfer MR contrast agents. Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. A modular strategy to prepare multivalent inhibitors of prostate-specific membrane antigen (PSMA).
#Dextran mr contrast free
Balanced steady-state free precession (bSSFP) from an effective field perspective: application to the detection of chemical exchange (bSSFPX). Accelerating chemical exchange saturation transfer (CEST) MRI by combining compressed sensing and sensitivity encoding techniques. Chemical exchange saturation transfer (CEST) imaging with fast variably-accelerated sensitivity encoding (vSENSE). Prostate-specific membrane antigen expression in normal and malignant human tissues. Antitumor properties and toxicity of dextran–methotrexate conjugates are dependent on the molecular weight of the carrier.
#Dextran mr contrast trial
Phase I clinical and pharmacokinetic trial of dextran conjugated doxorubicin (Ad-70, Dox-Oxd). Dextran 40 therapy made safer by pretreatment with dextran 1. Use of dextran nanoparticle: a paradigm shift in bacterial exopolysaccharide based biomedical applications. Sugar based biopolymers in nanomedicine new emerging era for cancer imaging and therapy. Anaphylactoid reactions to dextran 40 and 70: reports to the United States Food and Drug Administration, 1969 to 2004. Immunoglobulin class and subclass distribution of dextran‐reactive antibodies in human reactors and non reactors to clinical dextran. Pathomechanisms of dextran-induced anaphylactoid/anaphylactic reactions in man. Rational chemical design of the next generation of molecular imaging probes based on physics and biology: mixing modalities, colors and signals. Exchange-mediated contrast in CEST and spin-lock imaging. A review of the efficacy and safety of 7.5% NaCl/6% dextran 70 in experimental animals and in humans. Initial evaluation of DCFPyL for prostate-specific membrane antigen (PSMA)-targeted PET imaging of prostate cancer. Effect of chelators on the pharmacokinetics of 99mTc-labeled imaging agents for the prostate-specific membrane antigen (PSMA). Sequential SPECT and optical imaging of experimental models of prostate cancer with a dual modality inhibitor of the prostate-specific membrane antigen. Characterization of a targeted nanoparticle functionalized with a urea-based inhibitor of prostate-specific membrane antigen (PSMA). 2-(3-ureido)-pen tanedioic acid, DCFPyL, a PSMA-based PET imaging agent for prostate cancer. Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers. The hydrodynamic radii of macromolecules and their effect on red blood cell aggregation. In vivo imaging of glucose uptake and metabolism in tumors. Natural D-glucose as a biodegradable MRI contrast agent for detecting cancer. MRI detection of glycogen in vivo by using chemical exchange saturation transfer imaging (glycoCEST). A new class of contrast agents for MRI based on proton chemical exchange dependent saturation transfer (CEST). PSMA specific antibodies and their diagnostic and therapeutic use. Prostate-specific membrane antigen targeted protein contrast agents for molecular imaging of prostate cancer by MRI. Synthesis and evaluation of GdIII‐based magnetic resonance contrast agents for molecular imaging of prostate‐specific membrane antigen. PSMA-targeting iron oxide magnetic nanoparticles enhance MRI of preclinical prostate cancer. Magnetic resonance molecular imaging of the HER-2/neu receptor. Ferritin as an endogenous MRI reporter for noninvasive imaging of gene expression in C6 glioma tumors. Cancer cell targeting and imaging with biopolymer-based nanodevices. Bench to bedside molecular functional imaging in translational cancer medicine: to image or to imagine? Clin.
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